Human Extracellular superoxide dismutase [Cu-Zn]

Human extracellular superoxide dismutase (EC-SOD) is an enzyme that is involved in the detoxification of superoxide radicals, which are highly reactive oxygen species that can cause damage to cells. It is a member of the superoxide dismutase (SOD) family of enzymes, which play a role in the detoxification of superoxide radicals. EC-SOD is composed of a catalytic domain that is responsible for its enzymatic activity and a non-catalytic domain that is involved in its function.

EC-SOD plays a critical role in the detoxification of superoxide radicals by catalyzing the conversion of superoxide radicals into hydrogen peroxide, which can be further detoxified by other enzymes. EC-SOD has been found to be involved in a number of biological processes, including the regulation of inflammation and the prevention of oxidative stress.

There have been a number of recent research studies focused on EC-SOD and its role in disease development. For example, a study published in the journal Free Radical Biology and Medicine in 2021 found that targeting EC-SOD with small molecule inhibitors was effective in reducing oxidative stress and inflammation in preclinical models of cardiovascular disease. Another study published in the journal Antioxidants in 2020 found that targeting EC-SOD with small molecule inhibitors was effective in reducing oxidative stress and inflammation in preclinical models of Alzheimer's disease.