Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >96% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P08700 |
| Uniprot Entry Name | IL3_HUMAN |
| Gene Names | IL3 |
| Alternative Names | IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor |
| Expression Region | Full Length of Mature Protein (20-152aa(P27S)) |
| Molecular Weight | 15.0 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. |
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; FUNCTION |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | IL-3 family |
| Tissue Specificity | Activated T-cells, mast cells, natural killer cells. |
| Pathway | Jak-STATsignalingpathway |
QC Data
| Please contact us for specific QC data. |