Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens crystallin alpha B (CRYAB), transcript variant 1 (NM_001885). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P02511 |
| Entry Name | CRYAB_HUMAN |
| Gene Names | CRYAB CRYA2 HSPB5 |
| Alternative Gene Names | CRYA2 HSPB5 |
| Alternative Protein Names | Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 175 |
| Molecular Weight(Da) | 20159 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK |
Background
| Function | FUNCTION: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. |
| Pathway | |
| Protein Families | Small heat shock protein (HSP20) family |
| Tissue Specificity | Lens as well as other tissues (PubMed:838078, PubMed:2387586). Expressed in myocardial tissue (PubMed:28493373). {ECO:0000269|PubMed:2387586, ECO:0000269|PubMed:28493373, ECO:0000269|PubMed:838078}. |
QC Data
| Please contact us for specific QC data. |