Nanobody

In the dynamic field of life sciences, Variable Heavy-chain Domain (VHH)—also referred as single domain antibody (Sdab) or nanobody—is emerging as a powerful tool for researchers. Derived from the immune systems of camelid species like llamas and alpacas, this small, single-domain antibody offers unique advantages over traditional antibodies. It is revolutionizing several areas:

• Diagnostics and Imaging: Ideal for biomarker detection and imaging.
• Therapeutics: Explored for treating cancers, autoimmune diseases, and infections.
• Research Tools: Used in assays like Western blotting and immunofluorescence.

Figure. Comparison of Antibody and VHH

Key Benefits of VHH:

• Compact Size: At around 15 kDa, nanobody penetrates tissues more effectively, reaching targets that larger antibodies cannot.
• High Stability: Its robust structure ensures functionality under a range of conditions, making it ideal for diverse applications.
• Specificity and Affinity: Nanobody can be engineered to bind tightly and specifically to various targets, enhancing research accuracy.
• Ease of Production: Produced in microbial systems, VHH nanobody is cost-effective and scalable, facilitating rapid development.

Why Choose Our VHH Products?
At Echo Bio, we provide high-quality nanobody products tailored for life science research, including:

• Custom Development: Tailored nanobody specific to your research needs.
• Expert Support: Our team is here to help you maximize the potential of our products.
• Ready-to-Use Options: A catalog of pre-validated nanobody for various applications, including a wide range of Anti-tag VHH, primary, secondary VHH and fluorescent labeled VHH

Need a custom solution or help? Contact us today!
Email: info@echobiosystems.com 
Phone: 1-646-351-4812

Primary VHH Antibodies

We offer a comprehensive portfolio of primary VHH antibodies (Research Use Only), targeting a wide range of diseases, including cancers, autoimmune disorders, infections, and more. Need a custom solution? We specialize in tailored VHH antibody development – contact us today!

 Anti-Tag VHH Antibodies

Targeting a comprehensive range of tags (GFP, HA, Flag, MYC, MBP, GST, and more), we offer diverse conjugation options including Biotin, HRP, Agarose beads, Magnetic beads, and a spectrum of fluorescent dyes (Fluor488, 594, 647). Choose the perfect VHH antibody solution for your specific experimental needs.

Secondary VHH Antibodies

We provide high-performance secondary VHH targeting primary antibodies raised from diverse hosts (human, mouse, rat, rabbit, chicken, goat, sheep), across various serotypes, such as IgG, IgY and IgM and others. By leveraging our secondary nanobodies, you can achieve enhanced sensitivity, precision, and versatility in their protein detection and analysis workflows, particularly in high-resolution imaging applications, pushing the boundaries of scientific discovery.

Nanobody-Fc Fusion Protein