Silica Particles
Silica, or silicon dioxide (SiO2), particles feature controllable size, large surface area, and easy surface modification via silanol groups. They can be nonporous, mesoporous, hollow, or core-shell structured. Surfaces can be modified with groups like carboxylate or amine for bonding. Silica is applied in protein separation, drug delivery, imaging, and more. It has low water solubility that increases with high or low pH.
Key aspects of silica particles:
- Properties: Silica particles possess a controllable particle size, a large specific surface area, and an easily modified surface due to silanol groups (Si-OH). They also have good chemical properties, thermal stability, and biocompatibility.
- Types: Silica nanoparticles can be nonporous, mesoporous (MSN), hollow mesoporous (HMSN), or core-shell structured.
- Synthesis: They can be synthesized using methods like the Stöber method and the microemulsion method, resulting in sizes ranging from 10 to 500 nm. Adjusting reaction conditions can easily tune particle sizes.
- Surface Modification: The surface of silica particles can be modified with various functional groups like carboxylate, amine, or octadecyl, which allows for covalent bonding with other molecules.
- Applications: Silica particles are used in protein adsorption and separation, nucleic acid detection and purification, drug and gene delivery, imaging, and as theranostic platforms.
- Solubility: Silica has low solubility in water, but the solubility increases at pH values above 8 and below 3.
- Dispersibility: Silica particles can be dispersed in polar solvents such as water and ethanol.
Key Advantages of Our PS Particles:
- Broad Size Range: We offer an expansive selection of particle sizes, ensuring the perfect fit for your specific requirements. Whether you need the precision of nanoscale particles or the handling ease of larger microspheres, we have you covered.
- Surface Modification Expertise: various surface modification options, including functionalization with carboxyl, amino, hydroxyl, and other groups, allowing you to tailor the surface chemistry to your needs.
- Exceptional Monodispersity: Our proprietary manufacturing processes ensure exceptionally low polydispersity index (PDI) values, guaranteeing uniform particle size and consistent performance. This translates to consistent performance, reliable results, and minimized variability in your applications.
- Customizable Solutions: Beyond our standard product offerings, we specialize in developing custom particle solutions. Our team of expert scientists will collaborate with you to design and synthesize particles with specific sizes, surface functionalities, and other characteristics to meet your unique challenges. We thrive on innovation and are dedicated to helping you achieve your research or manufacturing goals.
- Quality Assurance: Our particles are manufactured under stringent quality control measures to ensure high purity, uniform size, and consistent performance
Functional Silia Particles
Plain | NH2 | COOH | Epoxy | Albumin |
Streptavidin | Avidin | Biotin | Ni-NTA | NTA |
NHS | Acrylate | Al2O3 | EDTA | Au |
NR3+ | SO3H | TiO2 | C18 | Protein A |
TMS |
Fluorescent Silia Particles
Green | Plain | NH2 | COOH | Streptavidin | Biotin |
Orange | Plain | NH2 | COOH | Streptavidin | Biotin |
Blue | Plain | NH2 | COOH | Streptavidin | Biotin |
Red | Plain | NH2 | COOH | Streptavidin | Biotin |